A. Inoue, M. Sugiura, Y. Tsuzuki
Jul 1, 1954
Citations
0
Influential Citations
6
Citations
Journal
Bulletin of the Chemical Society of Japan
Abstract
1) 8-Sulfoquinoline has been obtained with a yield of 80.3% by sulfonating quinoline with 50% oleum at 140°C for 2 hrs. 2) 8-Hydroxyquinoline has been synthesized by fusing 1 mole of 8-sulfoquinoline with 9 moles of NaOH at 300-315°C for 10 to 15 minutes, decomposing the with dilute sulfuric acid, neutralizing with sodium hydroxide and soda to a pH 7.2, and by distilling with steam for 1.5 hrs. The remaining 8-hydroxyquinoline in the residue and in the filtrate was collected in the form of its copper salt. The highest yield of 8-hydroxyquinoline including its copper salt was 84.14%. 3) Copper 8-hydroxyquinolinate has been obtained with a yield of nearly 100% by heating 8-hydroxyquinoline with 0.86 times its weight of crystalline copper sulfate together with a large quantity of water at 80° to 100°C.