Y. Masuda, T. Tashiro, K. Mori
Dec 27, 2006
Citations
0
Influential Citations
15
Citations
Journal
Tetrahedron-asymmetry
Abstract
Abstract (+)-Carpamic acid [(2′ R ,5′ S ,6′ S )-8-(5′-hydroxy-6′-methylpiperidin-2′-yl)octanoic acid, 1 ] was synthesized from ( S )-alanine, employing intramolecular and reductive amination of acyclic amino ketone 8 as the key step to generate the piperidine ring.