B. Bashyal, H. Chow, G. Fleet
1987
Citations
0
Influential Citations
33
Citations
Journal
Tetrahedron
Abstract
Abstract The efficient synthesis of 4S,5S-2-(N-benzyloxycarbonyl)amino-5,6-dihydroxyhex-2-en-4-olide (4) from D-glucuronolactone is described, the potential of (4) as a divergent intermediate for the synthesis of 2S,4S-4-hydroxy-α-amino acids is illustrated by the conversion of (4) to 2S,4S,5S-dihydroxypipecolic acid and bulgecinine [2S,4S,5R-4-Hydroxy-5-(hydroxymethyl)-proline].