S. N. Meyyanathan, M. Ramu, B. Suresh
Nov 1, 2010
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Influential Citations
9
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Journal
Medicinal Chemistry Research
Abstract
A new series of 2-methyl-3H-quinazolinones substituted at the third position with amino acids (2–5) and aryl amine (6, 7) was designed, synthesized, and analyzed by infrared, NMR, and mass spectral analysis. Further, the compounds were screened for their in vivo antimalarial activity using the rodent malaria parasite Plasmodium yoelii (N-67) with the Swiss mice model. The compounds were also tested for their antibacterial activity.