Huang Qiu-chan
2012
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Journal
Chemical Research and Application
Abstract
In this paper,S-methyl-iso-thiourea sulfate was synthesized using thiourea and dimethyl sulfate as starting materials.The creatinol sulfate was prepared by S-methyl-iso-thiourea sulfate and 2-methylaminoethanol.The base creatinol was liberated.Seven creatinol salts were obtained by the base creatinol reacting with biological substituted benzoic acids.Their structures had been determined by IR,1H NMR and elemental analysis.The preliminary biological activities had been tested.The results showed that most of them exhibited fungus-inhibiting.