Gong Ping
2006
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Quality indicators
Journal
Chinese Journal of Medicinal Chemistry
Abstract
Aim To design and synthesize a series of new ethyl 6-bromo-5-hydroxy-1H-indole-3-carboxylate derivatives,and to evaluate their antiviral activities in vitro.Methods Eleven new compounds were synthesized and their structures were confirmed by()~1H-NMR and MS.Their in vitro anti-influenza A3 virus and anti-RSV activities were tested.Results and conclusion The target compounds all exhibited antiviral activities.Among them,the antiviral activity of compound Ⅹ_9 was comparable to that of admantadine.