G. El‐Hiti, M. Abdel-megeed, Y. A. Mahmoud
May 1, 2000
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0
Influential Citations
4
Citations
Journal
ChemInform
Abstract
Condensation of equimolar amounts of 4-hydrazino-2-phenylquinazoline 1 and a number of monosaccharides 2 (D-glucose, D-galactose, D-xylose, D-arabinose and D-ribose) affords the corresponding hydrazones 3-7 in good yields. However, whem three molar equivalents of 1 is allowed to react with 2 in the presence of glacial acetic acid, the corresponding osazones 13-16 are obtained. Acetylation of the hydrazones 3-7 and osazones 13-16 give the corresponding acetyl derivatives 8-12 and 17-20. The products obtained have been characterised by spectral data and elemental analyses. Some of the compounds show antifungal and antibacterial activities.