Yi-An Ruan, Linhong Jin, Jiang He
May 31, 2011
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0
Influential Citations
5
Citations
Journal
African Journal of Pharmacy and Pharmacology
Abstract
A series of novel 1-(2,4-dichlorophenyl)-3-aryl-2-(1H-1,2,4-triazol-1-yl) prop-2en-1-one derivatives were synthesized in good yields by an aldol condensation between 1-(2,4-dichlorophenyl)-2-(1H-1,2, 4-triazol1-yl) ethanone and an aryl aldehyde. The structures were established through 1 H NMR and 13 C NMR spectroscopy and elemental analysis. All compounds 4a-l at a concentration of 50 mg/L showed inhibition against the growth of Gibberella zeae, Fusarium oxysporium, Cytospora mandshurica. The title compound 4a displayed high antifungal activities against G. zeae, F. oxysporium, C. mandshurica comparable to hymexazol.