K. Richardson, K. Brammer, S. Jevons
Oct 1, 1979
Citations
0
Influential Citations
8
Citations
Journal
The Journal of antibiotics
Abstract
1-N-(1,3-Dihydroxy-2-propyl)kanamycin B was prepared and its in vitro activity against aminoglycoside-sensitive and aminoglycoside-resistant organisms was compared with that of kanamycin B and gentamicin. This kanamycin B derivative (code No. UK-31,214) demonstrated potent activity in all of these tests and gave good protection in experimental infections in mice.