Alena L. Oleshchuk, Anastasiya A. Karbainova, T. Krivoruchko
Jan 1, 2019
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0
Influential Citations
10
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Journal
Chemistry of Heterocyclic Compounds
Abstract
Aldol-crotonic condensation reactions of 3,5-diacetyl-2,6-dimethylpyridine with various aldehydes were used to synthesize bisazachalcone derivatives, which were subsequently cyclized with hydrazine hydrate in acetic acid, leading to the respective bisderivatives of 4,5-dihydro-1H-pyrazole. The reactions of 3,5-diacetyl-2,6-dimethylpyridine with some hydrazides also provided the respective bishydrazones. The analgesic activity of the obtained derivatives was tested.