Kashinath Noubade, G.M.Channamma, T. Kumar
2009
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Journal
Organic Chemistry: An Indian Journal
Abstract
The reaction of 2-[(2,3-dimethylphenyl) amino] ethyl benzoate (1) with hydrazine hydrate in dry benzene gave 2-[(2,3-dimethylphenyl) amino] benzocarbohydrazide (2). Compound (2) upon treatment with substituted aromatic aldehydes to furnished the corresponding schiffÂs base (3a-e) which on treatment with acetyl chloride / with phenyl acetyl chloride and triethylamine in presence of dry benzene afforded 2-[2,3-dimethylphenyl amino)-NÂ-[2-oxo-4-(substituted phenyl) azetidine-1-yl]benzamide (4a-e) and 2-(2,3-dimethylphenyl amino)-NÂ-[2-oxo-3-phenyl-4-(substituted phenyl) azetidine-1-yl] benzamide (5a-e). All newly synthesized compounds were characterised on the basis of IR, 1HNMR and mass spectral data.