I. K. Moiseev, M. Zemtsova, P. L. Trakhtenberg
Dec 1, 1988
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0
Influential Citations
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Journal
Pharmaceutical Chemistry Journal
Abstract
Continuing work on the synthesis and examination of the biological activity of 2-R'-4-Rquinolines, it was considered desirable to develop convenient methods for the synthesis of 2-cycloalkylquinoline-4-carboxylic acids and their derivatives. In this connection, it was of importance to establish the influence of a cycloalkyl substituent in the 2-position of the quinoline ring on biological activity. This made it possible to compare the properties and biological activity of aryl, hetaryl, and cycloalkylquinolines.