Faycel Jemmezi, Fethi Bel Haj Kether, I. Amri
2014
Citations
0
Influential Citations
11
Citations
Journal
IOSR Journal of Applied Chemistry
Abstract
Potential biologically active derivatives of the 2- Amino-5-aryl or Formylpyridine-3-Carbonitriles (2a-d ) were prepared by the cyclocondensation reaction of vinamidinium salts with malonitrile. The structures of these compounds were established on the basis of elemental (C, H,N) and spectral ( 1 H-NMR, 13 C-NMR and spectral data) analysis. The compounds were screened for their antifungal and antibacterial activity. The compound 2-amino-5-formylpyridine-3-carbonitrile was found to be the most potent compound of series.