Mirta L. Fascio, C. Sepúlveda, E. Damonte
Jul 1, 2019
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Influential Citations
13
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Journal
Carbohydrate research
Abstract
Herein we describe the synthesis of imidazo[2,1-b][1,3,4]thiadiazoles from carbohydrates with D-ribo and D-xylo configuration. The antiviral activity of these compounds was tested against Junín virus (the etiological agent of Argentine hemorrhagic fever). The p-chlorophenyl derivatives showed antiviral activity in a range of micromolar concentration.