N. O. Saldabol, Y. Popelis, L. N. Alekseeva
Jun 1, 1977
Citations
0
Influential Citations
1
Citations
Journal
Pharmaceutical Chemistry Journal
Abstract
3-Nitro derivatives [I, 2] and especially 2-(5'-nitro-2'-furyl) derivatives [3-5] of imidazo[l,2-a]pyridine are known to possess antibacterial and antiprotozoal properties. We decided to trace the change in antibacterial properties through a series of derivatives of 2-(2'-furyl)imidazo[l,2-a]pyridine as a function of the nature and position of the substituents. We synthesized compounds of this series with substituents in position i, 3, 6, or 8 of the imidazopyridine system and in position 5 of the furan ring, together with some of their analogs.