K. Ramalingam, G. X. Thyvelikakath, K. Berlin
Jun 1, 1977
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Influential Citations
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Journal
Journal of medicinal chemistry
Abstract
A small series of pyrazoles and isoxazoles derived from thiochroman-4-one has been synthesized and characterized. The compounds were examined for their in vitro inhibitory activity against Bacillus subtilis and Pseudomonas fluorescens. Among the tested compounds the pyrazole derivative from thiochroman-4-one was found to be the most effective inhibitor of growth of B. subtilis. Extensive H NMR analysis was recorded for all compounds.