V. L. Gein, V. N. Vychegzhanina, E. B. Levandovskaya
Nov 3, 2010
Citations
0
Influential Citations
3
Citations
Journal
Pharmaceutical Chemistry Journal
Abstract
5-Aryl-4-acyl-3-hydroxy-1-(2,2-dimethoxyethyl)-3-pyrrolin-2-ones were synthesized by the reaction of acylpyruvic acid methyl esters with a mixture of an aromatic aldehyde and aminoacetaldehyde dimethylacetal. The proposed structures are confirmed by IR and PMR spectroscopy. The results of an investigation of the antibacterial and analgesic activity of the synthesized compounds are presented.