A. Grinev, E. K. Panisheva, A. A. Cherkvasova
Mar 1, 1987
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Journal
Pharmaceutical Chemistry Journal
Abstract
We have now synthesized some novel 5-methoxyindole-3-carboxylic acids with bromine in the 6-position of the ring (la, b). Decarboxylation of these compounds in quinoline has afforded 5-methoxy-6-bromolndoles with a free B-position (lla, b). These compounds, llke 4,5dimethoxy-6-bromoindole (llc) [2], are of interest as starting materials for the synthesis of analogs of biologically active compounds.