B. Modzelewska-Banachiewicz, B. Michalec, T. Kamińska
Apr 1, 2009
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0
Influential Citations
8
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Journal
Monatshefte für Chemie - Chemical Monthly
Abstract
Abstract(Z)-3-(3,4-diaryl-1,2,4-triazole-5-yl)prop-2-enoic acid derivatives were obtained in the course of the reaction of N3-substituted amidrazones with maleic anhydride, and isomerized into the (E) isomers by heating under reflux in acetic acid solution. The molecular structure of the compounds obtained was confirmed by IR and 1H NMR spectroscopy, and by X-ray crystallography for (2E)-3-(4,5-diphenyl-4H-1,2,4-triazol-3-yl)prop-2-enoic acid. The antiviral and immunomodulating activity of several of the compounds was examined.Graphical abstract