V. L. Gein, V. V. Mishunin, E. P. Tsyplyakova
Dec 1, 2009
Citations
0
Influential Citations
14
Citations
Journal
Pharmaceutical Chemistry Journal
Abstract
Eighteen methyl-7-aryl(heteryl)-6-(2-thienoyl)-4,7-dihydrotetrazolo[1,5-a]pyrimidine-5-carboxylates (I – XVIII) have been synthesized via the interaction of methyl esters of acylpyruvic acids with a mixture of aromatic or heterocyclic aldehydes and 5-aminotetrazole monohydrate. The proposed structures of the synthesized compounds were confirmed by IR spectroscopy and PMR spectrometry. Several compounds have been tested for antimicrobial activity.