D. Gruzdev, E. Chulakov, G. Levit
Nov 1, 2017
Citations
0
Influential Citations
13
Citations
Journal
Mendeleev Communications
Abstract
Novel purine and 2-aminopurine conjugates containing fragments of (S)-aspartic and (S)-glutamic acids with free α-functional groups attached via a 1,2-ethylenediamine linker at 6-position of the purine core, as well as their analogues with N9-(2-hydroxyethoxy)methyl substituent have been synthesized. Among the conjugates obtained, compounds exhibiting a significant antimycobacterial activity have been found.