S. Pattan, S. Babu, J. Angadi
2002
Citations
0
Influential Citations
5
Citations
Journal
Indian drugs
Abstract
A new series of various 7-Chloro-(6-fluorobenzothiazole)-2-amino(substituted) acetanilides (6a-f) have been synthesized by the condensation of 2-amino-6-fluoro-7-chlorobenzothiazole (2) with different substituted chloroacetamides derivatives (5a-f) in dry 1,4-dioxane and Triethylamine (TEA). The structure of the title compounds have been established on the basis of their elemental analysis and spectral (UV, IR, 1 H NMR) data. All the compounds have been screened for their antibacterial and antifungal activities. The compounds 6b, 6c, and 6e were found to possess promising antifungal activity.