S. A. Pogosyan, N. P. Grigoryan, R. Paronikyan
Dec 2, 2011
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0
Influential Citations
2
Citations
Journal
Pharmaceutical Chemistry Journal
Abstract
A series of new spiro-condensed indoles have been synthesized and the relationship between their chemical structure and biological activity has been established. Reduction of the oxo group in previously synthesized hydrochlorides of 2′-oxyindolin(5′-bromoindolin)-3?-spiro-1-(1,2,3,4-tetrahydro-β-carboline and 3-methyl-β-carboline followed by treatment with an ether solution of HCl leads to the dihydrochlorides of indolin-(5′-bromoindolin)-3′-spiro-1-(1,2,3,4-tetrahydro-β-carboline and 3-methyl-β-carboline.