Haiwei Xu, Chao-Fan Xu, Zi-qi Fan
Feb 1, 2013
Citations
0
Influential Citations
11
Citations
Journal
Bioorganic & medicinal chemistry letters
Abstract
Pulvinone and several 3-fluoro-4-morpholino substituted pulvinone derivatives were synthesized in five steps from a common precursor, phenyl acetic acid. Most of synthetic morpholine substituted pulvinones showed inhibitory activity against Esherichia coli. For the first time, the inhibition of pulvinone and its derivatives against Gram-negative bacteria was reported.