V. K. Salvi, D. Bhambi, J. Jat
Jan 29, 2007
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0
Influential Citations
13
Citations
Journal
Arkivoc
Abstract
In this study, a series of 2-[(4-substituted phthalazine-1-yl)alkyl]-1H-isoindole-1,3(2H)-diones 6a-d and 2-{2-[4-(1,3-dioxo-1,3-dihydro-2H-isoindole-2-yl-alkyl)1-oxo phthalazine-2(1H)yl]alkoxy}-1H-isoindole-1,3(2H)-diones 7a-d have been synthesized from phthalyl derivatives of amino acids 1a-b as starting material. The structures of these compounds were confirmed by IR, H NMR and Mass spectral studies. Synthesized compounds 6a-d and 7a-d showed significant antimicrobial activity.