M. S. Karthikeyan, D. J. Prasad, B. Poojary
Nov 15, 2006
Citations
7
Influential Citations
474
Citations
Quality indicators
Journal
Bioorganic & medicinal chemistry
Abstract
A series of 2,4-dichloro-5-fluorophenyl bearing Mannich base (4 and 5) was prepared from triazole Schiff bases (3) by aminomethylation with formaldehyde and secondary/substituted primary amines. All newly synthesized compounds were screened for their antimicrobial activity. Compounds 3c, 4c, 4e and 4f exhibited promising antibacterial and compounds 3c, 5c, 5e and 5f showed good antifungal activity.