Dl Mussoi, G. Boswell, N. B. Mehta
1996
Citations
0
Influential Citations
10
Citations
Quality indicators
Journal
European Journal of Medicinal Chemistry
Abstract
Summary A series of benzamides containing N,N,2-trimethyl-1,2-propane diamine as the amide moiety was synthesized. The compounds were evaluated in the maximal electroshock (MES) and pentylenetetrazol (metrazole, MET) screens for anticonvulsant activity. The 3,5-trifluoromethyl, 3,5-dichloro, and 3-bromo analogues proved to be either equipotent with or more potent than phenytoin.