M. Wujec, M. Pitucha, M. Dobosz
Sep 1, 2004
Citations
0
Influential Citations
57
Citations
Journal
Acta pharmaceutica
Abstract
In the reaction of hydrazide of thiophene-2-acetic acid (1) with isothiocyanates, the respective thiosemicarbazides 2a-g were obtained. Further cyclization with 2% NaOH led to formation of 4-substituted-3-(thiophene- 2-yl-methyl)-Delta2-1,2,4-triazoline-5-thiones (3a-g). These compounds showed promising antimycotic activity.