R. Hanselmann, Jiacheng Zhou, P. Ma
Oct 10, 2003
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0
Influential Citations
46
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Journal
The Journal of organic chemistry
Abstract
Isoxazolidines have been synthesized in diastereomeric excess up to 94% via a MgBr2-induced chelation-controlled 1,3-dipolar cycloaddition reaction with N-hydroxyphenylglycinol as a chiral auxiliary. The diastereomerically pure isoxazolidines were further transformed into cyclic and acyclic beta-amino acid derivatives.