Naoto Hama, T. Matsuda, Takaaki Sato
May 18, 2009
Citations
1
Influential Citations
65
Citations
Journal
Organic letters
Abstract
An enantioselective total synthesis of (-)-agelastatin A from (-)-2,3-O-isopropylidene-d-threitol is described. The sequential Overman/Mislow-Evans rearrangement of the allylic bistrichloroimidate is the key step, which efficiently installed a diaminohydroxy group.