Vasanti G.Yadav and, S. B. Chandalia
May 15, 1997
Citations
0
Influential Citations
4
Citations
Journal
Organic Process Research & Development
Abstract
Important perfumery aldehydes such as 10-undecenal could be synthesized by Rosenmund reduction. This reduction by hydrogen is usually effected in the presence of a supported Pd catalyst. The main by-product is the alcohol, and it is formed by the subsequent reduction of the aldehyde. This can be prevented by the use of a catalyst poison or regulator. The regulator deactivates the catalyst for the desired reaction and renders the repeated use of the catalyst difficult. However, reuse of the catalyst is of great industrial relevance, because the incidence of cost due to catalyst may be prohibitive if it is used for only a single run. Therefore, attempts to dispense with the use of a regulator acquire considerable significance. It may be possible to obtain very high selectivities to the aldehyde even in the absence of a regulator, provided that the temperature employed is about 30−40 °C and the reduction is carried out at atmospheric pressure, at which the rate of hydrogenolysis is acceptable. The present wo...