Gu Zhong-qiang
2007
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Journal
Chemical Intermediates
Abstract
Allyl chloroformate,a hydroxyl-protection reagent,was synthesized using phosgene and allyl alcohol as staring material. The reaction conditions was optimized and get a higher yield (94%). Preliminary tests showed that the new synthesized product was more practical in the protect ion of the 5-OH of avermectin to synthesis its derivetives.