D. Enders, K. Funabiki
Apr 7, 2001
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0
Influential Citations
48
Citations
Journal
Organic letters
Abstract
[reaction: see text] An efficient asymmetric synthesis of alpha-trifluoromethyl-substituted primary amines via nucleophilic 1,2-addition of alkyllithium reagents to trifluoroacetaldehyde SAMP- or RAMP-hydrazone followed by benzoylation and SmI(2)-promoted nitrogen-nitrogen single bond cleavage is described.