S. Pritz, M. Pätzel*, G. Szeimies
May 23, 2007
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0
Influential Citations
20
Citations
Journal
Organic & biomolecular chemistry
Abstract
The synthesis of the lipophilic chiral amino acid 1 bearing the bicyclo[1.1.1]pentane moiety is described. Linear and cyclic hexapeptides of the type Arg-Arg-Xaa-Yaa-Arg-Phe containing 1 instead of one or two tryptophan residues are prepared by solid phase peptide synthesis and the antimicrobial and hemolytic activity of the peptides obtained are discussed.