M. S. Shengeliya, V. Avramenko, L. Kuleshova
Aug 1, 1986
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0
Influential Citations
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Citations
Quality indicators
Journal
Pharmaceutical Chemistry Journal
Abstract
The authors study the replacement of the p-aminobenzoic acid (PABA) moiety. The authors synthesized an indole analog of folic acid, namely dimethyl N-(5-(2'-amino-4'-oxo-6'-pteridinyl)methylaminoindol-2-yl)glutamate. The physicochemical properties and the chemical shifts in the PMR spectra of the compounds obtained are shown. The examination of the compound for antitumor activity was carried out using rats and mice.