A. Foroumadi, N. Mohammadhosseini, S. Emami
Jan 1, 2007
Citations
0
Influential Citations
28
Citations
Journal
Archiv der Pharmazie
Abstract
A number of 7‐piperazinylquinolones carrying a functionalized 2‐(furan‐3‐yl)ethyl moiety attached to the piperazine ring have been synthesized and evaluated as antibacterial agents against a panel of Gram‐positive and Gram‐negative bacteria. Most of the synthesized compounds exhibited significant antibacterial activity, and this activity can be modulated through the nature of the functionality on ethyl spacer attached to piperazine ring and the type of side chain present at the N‐1 position of quinolone ring.