J. Kim, Hyeong Beom Park, B. Chung
2006
Citations
0
Influential Citations
16
Citations
Quality indicators
Journal
Bulletin of The Korean Chemical Society
Abstract
The synthesis of a new series of 1 -methylcarbapenems having 5-(1,2-disubstituted ethyl)pyrrolidine moiety are described. Their in vitro antibacterial activities against both Gram-positive and Gram-negative bacteria were tested and the effect of substituents on the pyrrolidine ring was investigated. Among them, compound (IIIc) having 1-methoxyimino-2-hydroxyethyl moiety showed the most potent antibacterial activity.