S. Riyadh, N. A. Kheder, Ahlam M. Asiry
Aug 24, 2013
Citations
0
Influential Citations
16
Citations
Journal
Monatshefte für Chemie - Chemical Monthly
Abstract
A facile and convenient synthesis of [1,2,3]triazole, [1,2,4]triazolo[5,1-c][1,2,4]triazine, and pyrazolo[5,1-c][1,2,4]triazine derivatives incorporating an antipyrin-4-yl or antipyrin-4-ylcarboxamide moiety via the versatile, readily accessible 2-cyano-N-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)acetamide is described. Structures of the synthesized compounds were elucidated by means of IR, 1H NMR, 13C NMR, and mass spectral data. The biological activity of the newly synthesized compounds was examined and some of them were found to possess anticancer and antimicrobial activities.Graphical abstract