B. B. Sokmen, Nurhan Gumrukcuoglu, Serpil Uğraş
Jan 11, 2013
Citations
1
Influential Citations
9
Citations
Quality indicators
Journal
Journal of Enzyme Inhibition and Medicinal Chemistry
Abstract
The methoxy substitued two novel bis triazole-schiff bases (6 a–b) were synthesized with 4-amino-3,5-diethyl-4H-1,2,4-triazole and various bis-aldehydes. Their amine derivatives prepared by reduced with NaBH4 (5 a–b). The obtained products 6 a–b and 7 a–b were identified by FT-IR, 1H-NMR, 13C-NMR. The bis triazole-schiff bases and amine derivatives were tested for antimicrobial activity using the agar diffusion technique against 11 bacteria. The synthesized compounds (6 a–b and 7 a–b) were screened for their antielastase, antiurease and antioxidant activities. The resuts showed that the synthesized compounds (6 a–b and 7 a–b) had effective antielastase and antiurease activities.