B. Ahmed, Habibullah, Shamshir Khan
Mar 15, 2011
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Influential Citations
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Quality indicators
Journal
Journal of Enzyme Inhibition and Medicinal Chemistry
Abstract
Novel 1,3,4-oxadizole derivatives containing the 1,4-dioxane ring system were synthesised starting from 2,3-dihydro-1,4-benzodioxane-2-carbohydrazide. The synthesised compounds were evaluated for antihepatotoxic activity against CCl4-induced hepatotoxicity in rats. Some compounds demonstrated a significant antihepatotoxic activity comparable to the standard drug Silymarin.