Y. Lou, Jin-hua Dong, Li-ying Xu
Jul 1, 2004
Citations
0
Influential Citations
0
Citations
Quality indicators
Journal
Yao xue xue bao = Acta pharmaceutica Sinica
Abstract
AIM To study the anti-inflammatory activity of N-(4-arylamidophenyl) methanesulfonamide derivatives. METHODS The target compounds were synthesized from p-nitroaniline via three steps and were evaluated for anti-inflammatory activity with the model of xylene-induced ear edema in mice. RESULTS Eleven compounds were obtained and confirmed by IR, 1HNMR and MS. Some compounds were shown to have significant anti-inflammatory activity. CONCLUSION N-(4-arylamidophenyl) methanesulfonamide showed appreciable anti-inflammatory activity.