D. H. Vyas, S. Tala, J. Akbari
Jun 1, 2009
Citations
0
Influential Citations
31
Citations
Journal
ChemInform
Abstract
2-Amino-3-cyano-6-(3,5-dibromo-4-methoxyphenyl)-4-aryl-pyridines 2a-i arc synthesized by the reaction of compounds (2E)-3-(3,5-dibromo-4-methoxyphenyl)-1-arylprop-2-en-1-one 1a-i with malononitrile in the presence of ammonium acetate. Condensation of compounds 1a-i with malononitrile in pyridine has yielded 2-amino-3-cyano-6-(3,5-dibromo-4-methoxyphenyl)-4-arylpyrans 3a-i. The constitution of all the synthesized compounds have been cstablished by elemental analyses, IR, 1 H NMR, and mass spectral data. All the compounds arc screened for their antitubercular and antimicrobial activities.