C. M. Jamkhandi, J. Disouza
Sep 28, 2012
Citations
0
Influential Citations
4
Citations
Quality indicators
Journal
Research Journal of Pharmacy and Technology
Abstract
Five novel [(1H-benzotriazol-1-ylacetyl)amino]acetic acid derivatives were synthesized by substituting corresponding amino acids on a reaction intermediate 1H-benzotriazol-1-ylacetyl chloride. The derivatives were characterized by physical, chemical parameters, TLC and spectral data. Synthesized derivatives from Ib to Vb were screened for anti microbial activity against, S. Aureus, B. Subtilis, E. coli, S. typhi, C Albicanse, A Niger. MIC was measured against norfloxacine and ketoconazole. Present study confirms the synthesized derivatives endowed with effective antimicrobial activities.