V. Mulwad, A. S. Hegde
Jun 16, 2009
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Journal
ChemInform
Abstract
3-Acetyl-4-hydroxy-2H[1]benzopyran-2-one 2a-d has been treated with bromodeoxybenzoin in NaOH, THF:HMPA to give 4H-2-benzoyl-3-hydroxy-3-methyl-2-phenyl 2,3-dihydrofuro[3,2-c] benzopyran-4-one 3a-d. This on treatment with aqueous HCl in presence of dioxane gives 4H-3-methyl-2-phenyl furo[3,2-c] benzopyran-4-one 4a-d through acid catalysed 1,2elimination. All compounds have been screened for antimicrobial activity. They do not show significant activity.