A. N. Mayekar, H. Yathirajan, B. Narayana
Jan 19, 2011
Citations
0
Influential Citations
16
Citations
Journal
International Journal of Chemistry
Abstract
A series of new 8-bromo-1,3-diaryl-2,3-dihydro-1H-naphth[1,2e][1,3]oxazines 2a-n are synthesized. 6-Bromonaphthol undergoes ring closure reaction with substituted aryl and heteroarylaldehydes to give naphthoxazine derivatives. Some of these are hydrolyzed to obtain aminobenzylnaphthols 3c,l which are further condensed with different aryl/heteroaldehydes to yield 4a-e. The structures of newly synthesized compounds are confirmed through elemental analysis, spectral studies and single crystal X-ray study. Compounds are screened for their antibacterial and antifungal activity. Some of them exhibited promising activity.