A. Gotsulya
May 31, 2020
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0
Influential Citations
4
Citations
Journal
Ankara Universitesi Eczacilik Fakultesi Dergisi
Abstract
Objective: The aim of the work was to develop effective methods for the synthesis of biologically active heterocyclic systems containing 1,2,4-triazole and pyrazole. Material and Method: Chemical structures of synthesized compounds were characterized with elemental analysis, IR, 1H-NMR, LC-MS techniques. The antiradical activity was evaluated using the 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activity assay. Result and Discussion: Developed optimal methods of obtaining of alkylderivatives of 5-(5-methyl-1H-pyrazol-3-yl)-4-phenyl-4H-1,2,4-triazole-3-thiol. A number of synthesized compounds showed moderate antiradical activity.