A. R. Saundane, bullet Katkar, Vijaykumar bullet
May 11, 2012
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0
Influential Citations
30
Citations
Journal
Medicinal Chemistry Research
Abstract
New indole analogues containing pyrido[2,3-d]pyrimidin-4-(3H)-ones (3a–i), pyrazolo[3,4-b]pyridin-3-amines (4a–i) and pyrido[2,3-d]pyrimidin-4-amines (5a–i) were synthesized using appropriate synthetic routes. These newly synthesized compounds were screened for their antimicrobial and antioxidant activities. Compounds 3a, 3g, 4c, 4h, 4i, 5a, 5c and 5f exhibited good antibacterial and antifungal activities. The compounds 3b, 3c, 3g, 4a, 4h, 4i and 5a exhibited good radical scavenging activity. Compounds 3a and 4d exhibited good metal chelating activity compare with standards.