J. Lien, Li‐Jiau Huang, Jih P. Wang
Dec 1, 1997
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0
Influential Citations
49
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Quality indicators
Journal
Bioorganic & medicinal chemistry
Abstract
A series of 2-substituted 3-chloro-1,4-naphthoquinones was synthesized, and the antiplatelet, antiinflammatory, and antiallergic activities of these compounds were evaluated. The structure-activity relationships in this series were also examined. Most of the 2-alkyl/arylcarboxamido derivatives of 3-chloro-1,4-naphthoquinone showed potent activities with similar trends in each of the activities evaluated.