Zhang Lin
2010
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Quality indicators
Journal
Journal of Henan University
Abstract
Objective:To synthesize methylnaringenin,acetylnaringenin and study their anti-tumor activities.Methods: The target compounds were synthesized by methylation and acetylation,iodomethane as methylated reagent,acetic anhydride as acylated reagent.The structure were confirmed through IR,ESI-MS and 1H-NMR;their anti-tumor activities were determined by the method of MTT.Results: 7,4′-dimethylnaringenin and 5,7,4′-tri-acetyl naringenin were identified and their inhibition rate to SMMC-CTT21is7.60% and 4.10% respectively.Conclusion: 7,4′-dimethylnaringenin and 5,7,4′-tri-acetyl naringenin have no anti-tumor activity.