Baohe Tian, Meizi He, Z. Tan
Mar 1, 2011
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0
Influential Citations
26
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Quality indicators
Journal
Chemical Biology & Drug Design
Abstract
N‐acylhydrazones containing glycine residue 3a–j and 8a–h were synthesized as HIV‐1 capsid protein assembly inhibitors. The structures of the novel N‐acylhydrazone derivatives were characterized using different spectroscopic methods. Antiviral activity demonstrated that compound 8c bearing 4‐methylphenyl moiety was the most active with low cytotoxicity.